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Lectures
1. What is bioinformatics?
Exercises
1. Primary databases
2. Secondary databases
3. Other biological databases
4. Analysis of biological sequences
5. Identification of specific sequence motifs
6. Pairwise alignment
7. BLAST and multiple sequence alignment
8. Protein motif identification
9. Molecular phylogeny
10. Visualization of biomacromolecules
Problem tasks
Tests
Test 1
Test 2
Databases
Integrated database systems:
SRS - Lion
SRS - EBI
Entrez
KEGG
Primary databases:
GenBank / EMBL / DDBJ
Entrez - Nucleotide
UniProt
Swiss-prot/TrEMBL
PIR
Entrez - Protein
Secondary databases:
PROSITE
PRINTS
Pfam
SMART
ProDom
InterPro
Databases of macromolecular structures:
PDB
MMDB (Entrez Structure)
CATH
SCOP
Specialized databases:
LIGAND
ENZYME
PATHWAY
Entrez - Genome
Entrez - Taxonomy
OMIM
PubMed/Medline
Last update: 13.01.2010
Authors: Matej Stano and Lubos Klucar, Institute of Molecular Biology, SAS Bratislava