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| 2. Secondary databases |
Introduction
Secondary databases comprise information about sequences from primary databases. This is particularly related to protein sequences.
Examples of secondary databases: - PROSITE – database of protein domains and families (sequence motifs)
- PRINTS – database of protein families (sequence fingerprints)
- Pfam – database of protein domains and families (HMM profiles)
Task no. 1 In the PROSITE database (part of integrated database system SRS) search out ribosomal protein L1 and try to find out: - what is the length of the sequence motif characteristic for this protein (number of AA)
- how many known proteins do comprise this motif
- how many ribosomal proteins do not comprise this motif
- at least one organism, for which 3D structure of this protein was determined
- what is the biological function of this protein
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